これ食べていい?
Can I eat this?

 駄目です。
No.

 ルーシー、それは食べ物じゃないぞ! 食べちゃ駄目だ!
Lucy, that's not food! Don't eat it [that]!

 駄目! それは食べられないの!
No! You can't eat that! / That's not edible!